Ribosomal protein S16



Ribosomal protein S16 (RPS16) is one of the 22 proteins which belong to the small subunit of the bacterial ribosome. It exhibits endonuclease activity. The images at the left and at the right correspond to one representative RPS16, i.e. the crystal structure of Ribosomal protein S16 from Thermus thermophilus (2zm6, chain P).

3D Structures of Ribosomal protein S16
Update June 2011

S16
3bn0 – RPS16 – Aquifex aeolicus

1emw – TtRPS16 – NMR - Thermus thermophilus

S16 in small ribosomal subunit
2zm6, 1n36, 1j5e, 3oge, 3ogy, 3ohc, 3ohd, 3ohy, 3oi0, 3oi2, 3oi4, 3oto - TtRPS16 in 30S ribosomal subunit+THX+16S RRNA – Thermus thermophilus

2vqe, 2vqf, 2uuc, 2e5l, 2uu9, 2uua, 2uub, 3pyn, 3pyq, 3pys, 3pyu - TtRPS16 in 30S ribosomal subunit+16S RRNA+RNA fragment

3kc4 – EcRPS16 in 30S ribosomal subunit - Escherichia coli

3i1m, 3i1o, 3df1, 3df3, 2vho, 2vhp, 2avy, 2aw7, 1pnx, 3oaq, 3oar, 3ofa, 3ofb, 3ofo, 3ofp, 3ofx, 3ofy, 3or9, 3ora - EcRPS16 in 30S ribosomal subunit+16S RRNA

1i94, 1fka - TtRPS16 in 30S ribosomal subunit+16S RRNA

1p87, 1p6g - EcRPS16 in 30S ribosomal subunit+16S RRNA – Cryo-EM

3bbn - RPS16 in 30S ribosomal subunit+16S RRNA – Cryo-EM – spinach

S16 in small + large ribosomal subunit
1ml5 - EcRPS16 in 30S ribosomal subunit+50S ribosomal subunit+THX+chain release factor 2+P-site tRNA+tRNA Phe+mRNA fragment+23S RRNA+5S RRNA+16S RRNA - EM

S16 in small ribosomal subunit+ chain release factor
3mr8, 3ms0 – TtRPS16 in 30S ribosomal subunit+THX+chain release factor 1+P-site tRNA+mRNA+16S RRNA

3d5a, 3d5c - TtRPS16 in 30S ribosomal subunit+THX+chain release factor 1+P-site tRNA+E-site tRNA+mRNA +16S RRNA

2b64 - TtRPS16 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA+chain release factor 1

2b9m - TtRPS16 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA+chain release factor 2

2x9r, 2x9t, 2wh1, 2wh3 - TtRPS16 in 30S ribosomal subunit+THX+chain release factor 2+P-site tRNA+mRNA +16S RRNA

3f1e, 3f1g - TtRPS16 in 30S ribosomal subunit+THX+chain release factor 2+P-site tRNA+E-site tRNA +16S RRNA

S16 in small ribosomal subunit+tRNA+mRNA
2hgi - TtRPS16 in 30S ribosomal subunit+16S RRNA+tRNA Phe+tRNA fMet

2hgp - TtRPS16 in 30S ribosomal subunit+16S RRNA+tRNA Phe+mRNA

2i2p, 2i2u - EcRPS16 in 30S ribosomal subunit+16S RRNA+tRNA Phe+mRNA

2hgr - TtRPS16 in 30S ribosomal subunit+16S RRNA+tRNA Phe+tRNA fMet+mRNA

1yl4 – TtRPS16 in 30S ribosomal subunit+ tRNA Phe+16S RRNA+THRS mRNA operator

1pns - EcRPS16 in 30S ribosomal subunit+ tRNA Phe+16S RRNA+mRNA

1xnq, 1xnr - TtRPS16 in 30S ribosomal subunit+THX+mRNA+tRNA anticodon+16S RRNA

S16 in small ribosomal subunit+A-site tRNA
2uxd, 2uxc - TtRPS16 in 30S ribosomal subunit+THX+A-site mRNA CGGG+tRNA anticodon+16S RRNA

1n32, 1n33 - TtRPS16 in 30S ribosomal subunit+THX+A-site mRNA fragment+tRNA anticodon+16S RRNA

1n34 - TtRPS16 in 30S ribosomal subunit+THX+A-site mRNA fragment +16S RRNA

1xmo, 1xmq - TtRPS16 in 30S ribosomal subunit+THX+A-site mRNA+tRNA anticodon+16S RRNA

2uxb - TtRPS16 in 30S ribosomal subunit+THX+A-site mRNA GGGU+tRNA anticodon+16S RRNA

S16 in small ribosomal subunit+P-site tRNA
3i8g - TtRPS16 in 30S ribosomal subunit+P-site tRNA+mRNA +16S RRNA

3i8h, 3i9b, 3i9d - TtRPS16 in 30S ribosomal subunit+THX+P-site tRNA+mRNA +16S RRNA

1ibk - TtRPS16 in 30S ribosomal subunit+THX+P-site mRNA fragment +16S RRNA

2wwl - EcRPS16 in 30S ribosomal subunit+Poly-Ala chain+P-site tRNA+mRNA +16S RRNA - Escherichia coli

3i1q - EcRPS16 in 30S ribosomal subunit+P-site tRNA hairpin+mRNA

3i1s, 3i1z, 3i21 - EcRPS16 in 30S ribosomal subunit+P-site tRNA hairpin+mRNA +16S RNA

S16 in small ribosomal subunit+A-site tRNA+P-site tRNA
1ibl, 1ibm - TtRPS16 in 30S ribosomal subunit+THX+A-site mRNA fragment+P-site mRNA fragment+tRNA anticodon+16S RRNA

S16 in small ribosomal subunit+P-site tRNA+E-site tRNA
2ow8 - TtRPS16 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA+mRNA +16S RRNA

2b9o - TtRPS16 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA

2qnh - TtRPS16 in 30S ribosomal subunit+THX+P-site tRNA+E-site tRNA+mRNA +16S RRNA

S16 in small ribosomal subunit+A-site tRNA+P-site tRNA+E-site tRNA
2gy9, 2gyb - EcRPS16 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA – Cryo-EM

1jgo, 1jgp, 1jgq, 1gix - TtRPS16 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+tRNA Phe+mRNA +16S RRNA

3e1a, 3e1c - EcRPS16 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA

S16 in small ribosomal subunit + antibiotics
1i95, 1i97, 2hhh, 2f4v - TtRPS16 in 30S ribosomal subunit+16S RRNA+antibiotic 1hnx, 1hnw, 1hnz, 1fjg – TtRPS16 in 30S ribosomal subunit+16S RRNA+mRNA fragment+antibiotic

2qbb, 2qb9, 1vs5, 1vs7, 2qan, 2qal, 2qou, 2qow, 2qoy, 2qp0, 2z4k, 2z4m  - EcRPS16 in 30S ribosomal subunit+16S RRNA+antibiotic

2j00, 2j02 - TtRPS16 in 30S ribosomal subunit+16S RRNA+paromomycin+P-site tRNA fMet+E-site tRNA Phe+mRNA

2wdg, 2wdh, 2wdk, 2wdm - TtRPS14 in 30S ribosomal subunit+THX+P-site tRNA+E-site tRNA+mRNA +16S RRNA+tRNA Phe+paromomycin

3knj, 3knh - TtRPS16 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA+viomycin

3knl, 3knn - TtRPS16 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA+capreomycin

S16 in small ribosomal subunit + ribosome recycling factor
2qbd, 2qbf - EcRPS16 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor

3r8n, 3r8o – EcRPS16 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor + mRNA + tRNA

2qbh, 2qbj - EcRPS16 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor+gentamicin

2v46, 2v48 - TtRPS16 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor+P-site tRNA Phe+mRNA+tRNA fMet

S16 in small ribosomal subunit + elongation factor
2wri, 2wrk, 2xsy, 2xuy - TtRPS16 in 30S ribosomal subunit+THX+P-site tRNA+mRNA +16S RRNA+elongation factor G

2wrn, 2wrq - TtRPS16 in 30S ribosomal subunit+THX+A-site tRNA+mRNA +16S RRNA+elongation factor TU-4

3fic - TtRPS16 in 30S ribosomal subunit+THX+A-site tRNA+P-site tRNA+E-site tRNA+mRNA codon+16S RRNA+elongation factor TU-A

3izv – EcRPS16 in 30S ribosomal subunit+A/T-site tRNA Phe +16S RRNA+elongation factor TU

3izw – EcRPS16 in 30S ribosomal subunit+A-site tRNA Phe +mRNA +16S RRNA+elongation factor TU

2y0u, 2y0w, 2y0y, 2y12, 2y10, 2y18, 2y14, 2y16 – TtRPS16 in 30S ribosomal subunit+THX+A-site tRNA+E-site tRNA+mRNA codon+16S RRNA+elongation factor TU

2xqd – TtRPS16 in 30S ribosomal subunit+THX+E-site tRNA+mRNA +16S RRNA+elongation factor TU-B

3fih - EcRPS16 in 30S ribosomal subunit+A-site tRNA Phe+P-site tRNA+mRNA +16S RRNA+elongation factor TU

3huw, 3huy - TtRPS16 in 30S ribosomal subunit+THX+tRNA-Met+mRNA +16S RRNA+elongation factor P

1s1h - yRPS16 in 40S ribosomal subunit+18S RRNA+elongation factor 2 – Cryo-EM – yeast

S16 in small ribosomal subunit + translation initiation factor
1i96 - TtRPS16 in 30S ribosomal subunit+THX+IF3+16S RRNA

1hr0 - TtRPS16 in 30S ribosomal subunit+THX+IF+16S RRNA

S16 in small ribosomal subunit + various proteins
3kiq, 3kis, 3kiu, 3kix - TtRPS16 in 30S ribosomal subunit+toxin RelE+16S RRNA

1voq, 1vos, 1vov, 1vox, 1voz - EcRPS16 in 30S ribosomal subunit+protein Y+16S RRNA

2xfz, 2xg1 - TtRPS14 in 30S ribosomal subunit+tRNA Phe+mRNA+colicin E3+16S RRNA

3jyv - RPS16+RPS0+RPS2+RPS3+RPS5+RPS9+RPS11+RPS13+RPS15+RPS14+RPS18+RPS20+RPS22+RPS23+RPS29+18S RRNA+RACK1+S19E+tRNA – Cryo-EM - Thermomyces lanuginosus

3j00 – EcRPS16 + 16S RRNA + FTSQ + apolipoprotein A-I

S16 in small 40S ribosomal subunit + various proteins
2zkq – RPS16 in 40S ribosomal subunit+RNA fragments+RACK1+18S RRNA

3iz6 – RPS16 in 40S ribosomal subunit+RACK1 – wheat – Cryo EM

3o2z, 3o30 – yRPS16 in 40S ribosomal subunit+18S RRNA+RACK1

S16 in part of small ribosomal subunit
3iy8 – EcRPS16+EcRPS5+EcRPS6+EcRPS8+EcRPS9+ EcRPS11+EcRPS12+EcRPS15+EcRPS17+EcRPS18+Leishmania taretolae mRNA